Is irradiation a justifiable treatment of choroidal melanoma? Analysis of published results.

Is radiation a justifiable treatment of choroidal melanoma?

Correspondence Is radiation a justifiable treatment of choroidal melanoma? SIR, The paper by W A Manschot and R van Strik (Br J Ophthalmol 1987; 71: 348-52) is of value as it stimulates thinking about the controversies in melanoma treatment, but it lacks important relevant data. The concept of tumour doubling time of the authors is an oversimplification, as they assume that there is only one gr...

Fulminant hepatic failure due to metastatic choroidal melanoma

Metastasis rates and sites after treatment for choroidal melanoma by proton beam irradiation or by enucleation

PURPOSE To investigate tumor thickness and location, the interval of time between treatment for choroidal melanoma (proton beam irradiation or enucleation) and diagnosis of metastatic disease, and rates and sites of metastasis. DESIGN Retrospective, interventional, noncomparative case series. METHODS Follow-up of 152 patients with primary choroidal melanoma, between 1992 and 2006 (14 years)...

An investigation into the photothermal effects of multi- functional gold coated Fe3O4 Nanoparticles in the presence of external magnetic field and NIR laser irradiation on model of melanoma cancer cell line B16F10 in C57BL/6 mice

Introduction: Photothermal therapy using gold nanoshells is one of cancer therapy methods. Gold nanoshells generally consist of a silica core and a thin gold shell. Fe3O4@Au core-shell can be used for magnetic targeted therapy. The objective of this study was investigation of the photothermal effects of magnetically targeted Fe3O4@Au NPs and NIR laser irradiation on model of me...

Effect of low level laser irradiation with vitamin A on cell viability and apoptosis induction of human skin melanoma

Background: Skin cancer is the most prevalent type of cancer and melanoma is the deadliest kind of skin cancer in the world. Due to enhanced induction of apoptosis and ROS levels, low-level lasers can be utilized to destroy skin cancer cells. Lasers are used to treat some skin lesions. Vitamin A is beneficial in the prevention and treatment of skin cancer. Vitamin A inhibits the pathway of canc...